Endocrine Abstracts

Devices for continuous glucose monitoring (CGM) measure interstitial glucose as a marker of changes in blood glucose. Although still lacking the accuracy of blood glucose meters, the CGM devices currently available have improved glucose control. The established technique of continuous subcutaneous insulin infusion (CSII) uses a portable electromechanical pump to mimic non-diabetic insulin delivery, infusing insulin at pre-selected rates. Essentially, a slow basal rate is achie...

Continuous glucose monitoring (CGM) has highlighted the gap that exists between our expectations of tight metabolic control and the realities of actually achieving this, particularly during type 1 diabetes pregnancy. Longitudinal measurements indicate that despite overall ‘good’ HbA1c levels, pregnant women with type 1 diabetes spend 8 h/day with blood glucose levels above the recommended targets. New closed-loop (CL) or artificial pancreas approaches integrate insul...